Int J Stomatol

Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (6): 724-726.doi: 10.7518/gjkq.2013.06.007

Previous Articles     Next Articles

Distribution and antimicrobial susceptibility of subgingival pathogenic bacteria in 68 patients with chronic periodontitis

Sun Qingzhong1, Ye Honglin2   

  1. 1. Dept. of Stomatology, Qingtongxia Hospital of Traditional Chinese Medicine in Ningxia, Qingtongxia 751600, China; 2. Dept. of Ophthalmology and Otorhinolaryngology, Qingtongxia Hospital in Ningxia, Qingtongxia 751600, China
  • Received:2013-03-25 Revised:2013-07-29 Online:2013-11-01 Published:2013-11-01

RichHTML

3

PDF (PC)

1525

Abstract:

Objective The present study aims to investigate the distribution and antimicrobial susceptibilities of subgingival pathogenic bacteria from patients with chronic periodontitis. Methods The putative periodontal pathogens were isolated from subgingival plaque in patients with chronic periodontitis. Antimicrobial susceptibility of the bacteriato ten antimicrobial agents was measured by the agar dilution technique. Results A total of 262 bacterial strains wereisolated from the subgingival plaques of 68 patients with chronic periodontitis. Among the 262 isolates, Porphyromon gingivalis(66.2%) and Prevotella melaninogenica(60.3%) were the most predominant, followed by Actinobacillus actinomycetemcomitan(55.9%), Fusobacterius nucleatum(51.5%), Peptostreptococcus(45.6%), and so on. The tested strainswere highly susceptible to nitro imidazole drugs, and their susceptibility rates to metronidazole, tinidazole, and ornidazolewere over 90%. All isolates were susceptible to amoxicillin/clavulanate. Approximately 51% to 78% of the isolates were susceptible to azithromycin, minocycline, and clindamycin. Susceptibility to penicillin and erythromycin were only 2.3%and 17.9%, respectively. Conclusion Porphyromon gingivalis and Prevotella melaninogenica were the most frequently isolated putative periodontal pathogens in patients with chronic periodontitis in the Xiaoba district of Qingtongxia City, Ningxia. Amoxicillin/clavulanate and nitro imidazole drugs are useful alternatives against anaerobic bacteria involved inperiodontitis.

Key words: chronic periodontitis, anaerobic bacteria, antimicrobial susceptibility

CLC Number: 

  • R 781.4+2

TrendMD: 
[1] Huang Peiqing,Peng Xian,Xu Xin. Volatile sulfur compounds and its role in the management of intra-oral halitosis [J]. Int J Stomatol, 2021, 48(5): 592-599.
[2] Qi Xiaoling,Gan Tingbin,Huang Jiao. Research progress on the relationship between chronic periodontitis and chronic kidney disease [J]. Int J Stomatol, 2021, 48(1): 18-22.
[3] Yuan Zhenying,Guan Cuiqiang,Nan Xinrong. Research progress on DNA methylation and oral disease [J]. Int J Stomatol, 2019, 46(4): 437-441.
[4] Qian Du,Biao Ren,Xuedong Zhou,Xin Xu. The microbial ecology of root caries [J]. Int J Stomatol, 2019, 46(3): 326-332.
[5] Huang Haixia, Lan Yuyan, Zhang Hao, Pan Lanlan, Guo Ling, Liu Min. Changes on periodontal index and inflammatory factor levels in gingival crevicular fluid after implant restoration in patients with chronic periodontitis [J]. Inter J Stomatol, 2018, 45(4): 396-402.
[6] Li Lin, Wang Dan, Zhao Manzhu, Tang Ming. Research progress on the correlation between chronic periodontitis and neurodegenerative diseases [J]. Inter J Stomatol, 2017, 44(5): 514-518.
[7] Lu Xiao, Weng Chunhui, Wang Jinming, Liu Shaojuan, Liu Qin, Lin Shan. Biofilm formation and antimicrobial susceptibility of Streptococcus mitis in response to luxS/AI-2 signaling [J]. Inter J Stomatol, 2017, 44(4): 411-420.
[8] Yang Chunyan, Shui Yanqing. Research progress on association between single nucleotide polymorphism and chronic periodontitis [J]. Inter J Stomatol, 2017, 44(4): 452-458.
[9] Zhao Hong, Wang Xinlin, Lü Zhi, Wang Dongqing, Su Jianrong. Microbiological community analysis by high-throughput sequencing of subgingival plaque in patients with chronic periodontitis before and after subgingival scaling and root planing [J]. Inter J Stomatol, 2017, 44(3): 294-300.
[10] Wang Cancan, Yuan Hongmei, Chen Wen. Application of periodontal endoscope and nursing in perioscopy [J]. Inter J Stomatol, 2016, 43(2): 134-136.
[11] Liu Qiong, Xie Hao, Sun Jiang. Comparison of clinical effects in ultrasonic system and periodontal flap surgery in a short time [J]. Inter J Stomatol, 2016, 43(2): 159-164.
[12] Lin Mu, Ren Xiuyun, Chang Le, Yue Zijie, Shi Xuexue, Sun Lili.. Detection of Porphyromonas gingivalis in SD rats with chronic periodontitis [J]. Inter J Stomatol, 2013, 40(5): 572-576.
[13] Miao Yu, Zhang Xiaomin, Li Li.. Relationship of Epstein-Barr virus and human herpes virus-6 to chronic periodontitis [J]. Inter J Stomatol, 2012, 39(1): 117-119.
[14] YANG Heng, PAN Lun-hong, DING Yi. Research progress of matrix metalloprotease-13 [J]. Inter J Stomatol, 2009, 36(5): 561-563.
[15] DENG Hui, WU Ya-fei. Association between Porphyromonas gingivalis and atherosclerosis [J]. Inter J Stomatol, 2009, 36(4): 438-440.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[7] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[8] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[9] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[10] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .