Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (4): 557-560.doi: 10.7518/gjkq.2013.04.042

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Biological mechanisms of low intensity pulsed ultrasound on bone treatment

Xiao Weixiong, Ban Zhaoyang, Zhu Zhimin.   

  1. State Key Laboratory of Oral Diseases, Dept. of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2012-08-19 Revised:2013-03-12 Online:2013-07-01 Published:2013-07-01

Abstract:

Low intensity pulsed ultrasound(LIPUS), as a non-invasive bone healing method, can improve the healing of fresh fracture and distraction osteogenesis, decrease the healing time with significant result. The molecular mechanism of LIPUS remains to be a research hotspot. This review explores the mechanism how the low-intensity pulsed ultrasound works on cell signal transformation and summaries its clinical studies and molecular biological mechanisms.

Key words: low intensity pulsed ultrasound, fracture, osteoblast, extracellular signal-regulated kinase


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