Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (6): 794-796.doi: 10.3969/j.issn.1673-5749.2012.06.024

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Gingipain and its pathogenicity

Feng Qin1，2, Zhang Fengqiu1.   

  1. 1. Dept. of Periodontics and Mucosa Disease, The Affiliated Beijing Stomatological Hospital of Capital Medical University, Beijing 100050, China; 2. Dept. of Stomatology, General Hospital of Beijing Jingmei Group, Beijing 102300, China
  • Received:2012-03-03 Revised:2012-08-27 Online:2012-11-01 Published:2012-11-01

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Abstract:

Porphyromonas gingivalis（P.gingivalis） is recognized as the most important pathogen of periodontitis. Gingipain is thought to be one of the most important virulence factors of P.gingivalis. This paper reviews gingipain and its effects on the growth and adhesion of bacteria, tissue destruction and host defence mechanism.

Key words: Porphyromonas gingivalis, gingipain, pathogenicity, effect


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