国际口腔医学杂志

国际口腔医学杂志 ›› 2021, Vol. 48 ›› Issue (3): 322-328.doi: 10.7518/gjkq.2021051

• 综述 • 上一篇    下一篇

可降解医用镁基金属生物材料的研究进展

陈克难(),郭传瑸()   

  1. 北京大学口腔医学院 北京 100081
  • 收稿日期:2020-11-12 修回日期:2021-01-22 出版日期:2021-05-01 发布日期:2021-05-14
  • 通讯作者: 郭传瑸
  • 作者简介:陈克难,学士,Email: chenkenan@pku.edu.cn

Research progress on biodegradable medical magnesium-based materials

Chen Kenan(),Guo Chuanbin()   

  1. Peking University School of Stomatology, Beijing 100081, China
  • Received:2020-11-12 Revised:2021-01-22 Online:2021-05-01 Published:2021-05-14
  • Contact: Chuanbin Guo

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摘要：

作为可降解生物材料,镁及镁合金具有良好的生物相容性、较小的密度、更接近骨的弹性模量、促进成骨及一定的抗感染能力等优点,在生物医用材料领域具有广阔应用前景。但是镁基金属存在降解速率过高、不均匀腐蚀导致机械完整性丧失、降解产气等缺点,这也是镁及其合金投入临床应用的难点,近年的研究致力于通过合金化和表面改性改善镁合金的微观结构进而改善其腐蚀性能和机械性能。本文就镁基金属在口腔颌面部及其他医学领域的研究进展进行综述。

关键词: 可降解生物材料, 医用镁基金属, 临床应用

Abstract:

As biodegradable biomaterials, magnesium and its alloys have good biocompatibility and low density, have similar elastic modulus as that of bone, promote osteogenesis and have certain anti-infective ability. Therefore, these materials have broad application prospect in the field of biomedical materials. However, magnesium-based materials have some defects, such as rapid corrosion rate and loss of mechanical integrity because of pitting corrosion and gas generation, which limit their application. Current research has devoted to improve the corrosion and mechanical properties of magnesium alloys through alloying and surface modification. This article provides a brief review on the research progress of magnesium-based materials in the oral and maxillofacial field and other medical fields.

Key words: biodegradable materials, medical magnesium-based metal, medical application

中图分类号: 

  • R782
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