国际口腔医学杂志 ›› 2019, Vol. 46 ›› Issue (3): 253-257.doi: 10.7518/gjkq.2019035

• 信号通路专栏 • 上一篇    下一篇

白细胞介素-1α信号通路在牙萌出中的研究

蒙明梅,郭维华,周学东,邹静()   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心四川大学华西口腔医院儿童口腔科 成都 610041
  • 收稿日期:2018-07-27 修回日期:2019-02-25 出版日期:2019-05-01 发布日期:2019-06-05
  • 通讯作者: 邹静
  • 作者简介:蒙明梅,博士,Email:986321423@qq.com
  • 基金资助:
    四川省科学技术厅国际科技创新合作/港澳台科技创新合作项目(2019YFH0025)

Researches on interleukin-1α signalling pathway in tooth eruption

Mingmei Meng,Weihua Guo,Xuedong Zhou,Jing Zou()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2018-07-27 Revised:2019-02-25 Online:2019-05-01 Published:2019-06-05
  • Contact: Jing Zou
  • Supported by:
    This study was supported by International Cooperation in Science and Technology Innovation/Cooperation Program in Science and Technology Innovation of Hong Kong, Macao and Taiwan, Science and Technology Department of Sichuan Province(2019YFH0025)

摘要:

牙萌出是发育中的牙齿穿过牙槽骨和口腔黏膜到达功能位置的复杂生理过程,其间牙槽骨、牙囊、破骨细胞、成骨细胞及多种细胞因子等共同参与该过程。白细胞介素(IL)-1α是具有特殊生理意义的双重功能细胞因子。本文就IL-1α信号通路在牙萌出中的研究进行综述。

关键词: 牙萌出, 白细胞介素-1α, 牙囊

Abstract:

Tooth eruption, the process of the migration of the tooth crown from its site of development within bone to its functional position, is a complicated physiological course, involving alveolar bone, dental sac, osteoclasts, osteoblasts and multiple cytokines. Interleukin (IL)-1α is one of the dual-function cytokines which has a wide range of biological activities. This review is to address the researches on IL-1α signalling pathway in tooth eruption.

Key words: tooth eruption, interleukin-1α, dental sac

中图分类号: 

  • Q257
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