国际口腔医学杂志

国际口腔医学杂志 ›› 2019, Vol. 46 ›› Issue (1): 43-47.doi: 10.7518/gjkq.2019.01.008

• 综述 • 上一篇    下一篇

胚胎小鼠颌下腺分支形态发生及其影响因素

刘志凯,王淳艺,李春洁()   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院头颈肿瘤外科 成都 610041
  • 收稿日期:2018-04-15 修回日期:2018-08-02 出版日期:2019-01-01 发布日期:2019-01-11
  • 通讯作者: 李春洁
  • 作者简介:刘志凯,学士,Email：liuzhikai2015@qq.com
  • 基金资助:
    国家自然科学基金(81500807)

Research progress on submandibular gland branching-morphogenesis and its influencing factors in embryonic mice

Zhikai Liu,Chunyi Wang,Chunjie Li()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Head and Neck Tumor Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2018-04-15 Revised:2018-08-02 Online:2019-01-01 Published:2019-01-11
  • Contact: Chunjie Li
  • Supported by:
    This study was supported by National Natural Science Foundation of China(81500807)

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摘要：

颌下腺作为重要的唾液腺组成部分,其临床相关实验与器官重构的意义在近年来越发受到重视。本文综述了近年来国内外颌下腺的研究进展,介绍了颌下腺分支形态发生的基本概念,分析了分支形态发生过程中相关的影响因素,包括生长因子、激素、微小RNA等多个方面。

关键词: 颌下腺, 分支形态发生, 表皮生长因子, 成纤维细胞生长因子, 微小RNA

Abstract:

As an important part of salivary glands, submandibular gland’s significance of clinical experiments and organ reconstruction is drawing more attention in recent years. In this paper, starting from the research status at abroad, we point out the submandibular gland and its basic concepts of branching morphogenesis. Then we introduce the relevant factors of affecting research in recent years such as the growth factors, hormone and micro RNA, etc..

Key words: submandibular gland, branching-morphogenesis, epidermal growth factor, fibroblast growth factor, microRNA

中图分类号: 

  • R782
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