国际口腔医学杂志 ›› 2017, Vol. 44 ›› Issue (6): 636-641.doi: 10.7518/gjkq.2017.06.003
王志强1,2, 马丽娟1,2, 周海静3, 杨兰2, 聂红兵3, 薛龙2
Wang Zhiqiang1,2, Ma Lijuan1,2, Zhou Haijing3, Yang Lan2, Nie Hongbing3, Xue Long2
摘要: 益生菌作为一类对宿主有益的活性微生物,表现出诸多对宿主的益生性。抗肿瘤作用作为其益生性的一个重要方面,近年来备受国内外学者的关注。本文对益生菌抗肿瘤作用及其机制的研究进展进行概述。
中图分类号:
[1] Fuller R. Probiotics in man and animal[J]. J Appl Bacteriol, 1989, 66(5):365-378. [2] Veld JI, Havenaar R, Marteau P. Establishing a scientific basis for probiotic R&D[J]. Trends Biote-chnol, 1994, 12(1):6-8. [3] Food and Agriculture Organisation of the United Nations, World Health Organisation. Guidelines for the evaluation of probiotics in food[R]. London (Canada): Food and Agriculture Organisation of the United Nations and World Health Organisation, 2002. [4] Agostoni C, Axelsson I, Goulet O, et al. Prebiotic oligosaccharides in dietetic products for infants: a commentary by the ESPGHAN Committee on Nutri-tion[J]. J Pediatr Gastroenterol Nutr, 2004, 39(5): 465-473. [5] Fijan S. Microorganisms with claimed probiotic properties: an overview of recent literature[J]. Int J Environ Res Public Health, 2014, 11(5):4745-4767. [6] Young J, Tardy V, Perrière AL, et al. Probiotics—from metchnikoff to bioactives[J]. Int Dairy J, 2008, 18(7):714-728. [7] Lichtenstein L, Avni-Biron I, Ben-Bassat O. Probio-tics and prebiotics in Crohn’s disease therapies[J]. Best Pract Res Clin Gastroenterol, 2016, 30(1):81- 88. [8] Grant MC, Baker JS. An overview of the effect of probiotics and exercise on mood and associated health conditions[J]. Crit Rev Food Sci Nutr, 2016: 1189872. [9] 郭曼丽, 聂红兵, 周海静. 乳酸杆菌在口腔中益生特性的研究[J]. 重庆医学, 2015, 44(10):1408-1410. Guo ML, Nie HB, Zhou HJ. Study on probiotic pro-perties of Lactobacillus in oral cavity[J]. Chongqing Med, 2015, 44(10):1408-1410. [10] 孙小华, 付英. 益生菌与人体健康研究[J]. 中国卫生产业, 2015, 12(21):162-164. Sun XH, Fu Y. Progress in the human health effects of probiotics[J]. Chin Health Ind, 2015, 12(21):162- 164. [11] Zhong L, Zhang X, Covasa M. Emerging roles of lactic acid bacteria in protection against colorectal cancer[J]. World J Gastroenterol, 2014, 20(24):7878- 7886. [12] Plottel CS, Blaser MJ. Microbiome and malignancy [J]. Cell Host Microbe, 2011, 10(4):324-335. [13] Abreu MT, Peek RM Jr. Gastrointestinal malignancy and the microbiome[J]. Gastroenterology, 2014, 146 (6):1534-1546. [14] Soltan Dallal MM, Mojarrad M, Baghbani F, et al. Effects of probiotic Lactobacillus acidophilus and Lactobacillus casei on colorectal tumor cells activity (CaCo-2)[J]. Arch Iran Med, 2015, 18(3):167-172. [15] Chen ZF, Ai LY, Wang JL, et al. Probiotics Clos - tridium butyricum and Bacillus subtilis ameliorate intestinal tumorigenesis[J]. Future Microbiol, 2015, 10(9):1433-1445. [16] 梁素妨, 许琳, 王静, 等. 胃癌和结肠癌小肠细菌过度生长情况分析[J]. 中国微生态学杂志, 2015, 27 (12):1417-1420. Liang SF, Xu L, Wang J, et al. Small intestinal bacterial overgrowth in patients with gastrointestinal cancer[J]. Chin J Microecol, 2015, 27(12):1417- 1420. [17] Candela M, Turroni S, Biagi E, et al. Inflammation and colorectal cancer, when microbiota-host mutua-lism breaks[J]. World J Gastroenterol, 2014, 20(4): 908-922. [18] Hardy H, Harris J, Lyon E, et al. Probiotics, prebio-tics and immunomodulation of gut mucosal defences: homeostasis and immunopathology[J]. Nutrients, 2013, 5(6):1869-1912. [19] Romano M, Ricci V, Zarrilli R. Mechanisms of disease: Helicobacter pylori -related gastric carcino-genesis—implications for chemoprevention[J]. Nat Clin Pract Gastroenterol Hepatol, 2006, 3(11):622- 632. [20] 杨茜洋, 王绪明. 乳腺癌的风险评估及治疗[J]. 江汉大学学报(自然科学版), 2016, 44(2):179-183. Yang QY, Wang XM. Risk assessment and treatment of breast cancer[J]. J Jianghan Univ(Nat Sci Ed), 2016, 44(2):179-183. [21] 张红霞. 乳腺癌术后患者生活质量的影响因素分析[J]. 解放军护理杂志, 2007, 24(3):45-46. Zhang HX. Influencing factors of quality of life in patients with breast cancer after operation[J]. Nurs J Chin PLA, 2007, 24(3):45-46. [22] Hassan Z, Mustafa S, Rahim RA, et al. Anti-breast cancer effects of live, heat-killed and cytoplasmic fractions of Enterococcus faecalis and Staphyloco - ccus hominis isolated from human breast milk[J]. In Vitro Cell Dev Biol Anim, 2016, 52(3):337-348. [23] Aragón F, Carino S, Perdigón G, et al. The adminis-tration of milk fermented by the probiotic Lacto-bacillus casei CRL 431 exerts an immunomodula-tory effect against a breast tumour in a mouse model [J]. Immunobiology, 2014, 219(6):457-464. [24] Motevaseli E, Shirzad M, Akrami SM, et al. Normal and tumour cervical cells respond differently to vaginal lactobacilli, independent of pH and lactate [J]. J Med Microbiol, 2013, 62(Pt 7):1065-1072. [25] de Moreno de LeBlanc A, Matar C, Farnworth E, et al. Study of cytokines involved in the prevention of a murine experimental breast cancer by kefir[J]. Cyto-kine, 2006, 34(1/2):1-8. [26] De MA, Matar C, Thériault C, et al. Effects of milk fermented by Lactobacillus helveticus R389 on im-mune cells associated to mammary glands in normal and a breast cancer model[J]. Immunobiology, 2005, 210(5):349-358. [27] Zoa-Assoumou S, Ndjoyi-Mbiguino A, Mabika BM, et al. Human papillomavirus genotypes distribution in cervical cancer cases in Gabon[J]. Infect Agent Cancer, 2016, 11(1):42. [28] Zoa-Assoumou S, Ndjoyi-Mbiguino A, Mabika MB, et al. Human papillomavirus genotypes distribution among Gabonese women with normal cytology and cervical abnormalities[J]. Infect Agent Cancer, 2016, 11(1):2. [29] Nami Y, Abdullah N, Haghshenas B, et al. Assess-ment of probiotic potential and anticancer activity of newly isolated vaginal bacterium Lactobacillus plantarum 5BL[J]. Microbiol Immunol, 2014, 58(9): 492-502. [30] 肖世全, 张培炽, 田玉静. 以卡铂或顺铂为主联合化疗治疗晚期肺癌疗效及毒性比较[J]. 中国肿瘤临床与康复, 1996(s1):57-59. Xiao SQ, Zhang PZ, Tian YJ. Comparison of effi-cacy and toxicity of carboplatin combined with cis-platin in the treatment of advanced lung cancer[J]. Chin J Clin Oncol Rehab, 1996(s1):57-59. [31] 张梅春, 胡成平. 肺癌顺铂耐药的分子机制[J]. 国际呼吸杂志, 2006, 26(2):152-155. Zhang MC, Hu CP. The molecular basis for cisplatin resistance in lung cancer[J]. Int J Resp, 2006, 26(2): 152-155. [32] Gui QF, Lu HF, Zhang CX, et al. Well-balanced commensal microbiota contributes to anti-cancer response in a lung cancer mouse model[J]. Genet Mol Res, 2015, 14(2):5642-5651. [33] Gollwitzer ES, Marsland BJ. Microbiota abnorma-lities in inflammatory airway diseases—potential for therapy[J]. Pharmacol Ther, 2014, 141(1):32-39. [34] Mortaz E, Adcock IM, Folkerts G, et al. Probiotics in the management of lung diseases[J]. Mediators Inflamm, 2013(7350):751068. [35] Bosch M, Nart J, Audivert S, et al. Isolation and characterization of probiotic strains for improving oral health[J]. Arch Oral Biol, 2012, 57(5):539-549. [36] 钟来平, 孙坚, 郭伟, 等. 256例局部晚期口腔癌的生存分析[J]. 中国肿瘤临床, 2015, 42(4):217-221. Zhang LP, Sun J, Guo W, et al. Survival analysis of 256 patients with oral cancer[J]. Chin J Clin Oncol, 2015, 42(4):217-221. [37] Zhang M, Wang F, Jiang L, et al. Lactobacillus sa - livarius REN inhibits rat oral cancer induced by 4- nitroquioline 1-oxide[J]. Cancer Prev Res(Phila), 2013, 6(7):686-694. [38] Maekawa T, Hajishengallis G. Topical treatment with probiotic Lactobacillus brevis CD2 inhibits experimental periodontal inflammation and bone loss[J]. J Periodontal Res, 2014, 49(6):785-791. [39] 李博磊, 李龙江, 周学东, 等. 口腔微生物与口腔癌[J]. 口腔医学研究, 2015(6):558-563. Li BL, Li LJ, Zhou XD, et al. Oral microorganisms and oral cancer[J]. J Oral Sci Res, 2015(6):558-563. [40] Yang H, Zhao X, Tang S, et al. Probiotics reduce psychological stress in patients before laryngeal can-cer surgery[J]. Asia Pac J Clin Oncol, 2016, 12(1):e92-e96. [41] Dimitrovski D, Cencic A, Winkelhausen EA. Lacto - bacillus plantarum extracellular metabolites: in vitro assessment of probiotic effects on normal and cance-rogenic human cells[J]. Inter Dairy J, 2014, 39(2): 293-300. [42] Ki Y, Kim W, Nam J, et al. Probiotics for rectal volume variation during radiation therapy for pros-tate cancer[J]. Int J Radiat Oncol Biol Phys, 2013, 87(4):646-650. [43] Ray K. Diagnosis: programmed probiotics light up liver cancer in urine[J]. Nat Rev Gastroenterol Hepa-tol, 2015, 12(8):429. [44] Mandair DS, Rossi RE, Pericleous M, et al. The im-pact of diet and nutrition in the prevention and pro-gression of hepatocellular carcinoma[J]. Expert Rev Gastroenterol Hepatol, 2014, 8(4):369-382. [45] Mandair D, Rossi RE, Pericleous M, et al. Prostate cancer and the influence of dietary factors and sup-plements: a systematic review[J]. Nutr Metab(Lond), 2014, 11(1):30. [46] Kukkonen K, Kuitunen M, Haahtela T, et al. High intestinal IgA associates with reduced risk of IgE-associated allergic diseases[J]. Pediatr Allergy Im-munol, 2010, 21(1 Pt 1):67-73. [47] Dong H, Rowland I, Tuohy KM, et al. Selective ef-fects of Lactobacillus casei Shirota on T cell activa-tion, natural killer cell activity and cytokine produc-tion[J]. Clin Exp Immunol, 2010, 161(2):378-388. [48] Iyer C, Kosters A, Sethi G, et al. Probiotic Lacto - bacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modula-tion of NF-kappaB and MAPK signalling[J]. Cell Microbiol, 2008, 10(7):1442-1452. [49] Maroof H, Hassan ZM, Mobarez AM, et al. Lacto - bacillus acidophilus could modulate the immune response against breast cancer in murine model[J]. J Clin Immunol, 2012, 32(6):1353-1359. [50] Hu J, Wang C, Ye L, et al. Anti-tumour immune effect of oral administration of Lactobacillus plan - tarum to CT26 tumour-bearing mice[J]. J Biosci, 2015, 40(2):269-279. [51] Lammers KM, Brigidi P, Vitali B, et al. Immunomo-dulatory effects of probiotic bacteria DNA: IL-1 and IL-10 response in human peripheral blood mononu-clear cells[J]. FEMS Immunol Med Microbiol, 2003, 38(2):165-172. [52] Peterson CT, Sharma V, Elmén L, et al. Immune homeostasis, dysbiosis and therapeutic modulation of the gut microbiota[J]. Clin Exp Immunol, 2015, 179(3):363-377. [53] Lakritz JR, Poutahidis T, Levkovich T, et al. Bene-ficial bacteria stimulate host immune cells to coun-teract dietary and genetic predisposition to mammary cancer in mice[J]. Inter J Cancer, 2014, 135(3):529- 540. [54] Ghoneim MA, Moselhy SS. Antioxidant status and hormonal profile reflected by experimental feeding of probiotics[J]. Toxicol Ind Health, 2016, 32(4): 741-750. [55] Nébot-Vivinus M, Harkat C, Bzioueche H, et al. Multispecies probiotic protects gut barrier function in experimental models[J]. World J Gastroenterol, 2014, 20(22):6832-6843. [56] Burns AJ, Rowland IR. Antigenotoxicity of pro-biotics and prebiotics on faecal water-induced DNA damage in human colon adenocarcinoma cells[J]. Mutat Res, 2004, 551(1/2):233-243. [57] Zhu K, Hölzel CS, Cui Y, et al. Probiotic bacillus cereus strains, a potential risk for public health in China[J]. Front Microbiol, 2016, 7(560):718. [58] Floch MH. Probiotic safety and risk factors[J]. J Clin Gastroenterol, 2013, 47(5):375-376. |
[1] | 夏溦瑶,贾仲林. 维生素与唇腭裂发生相关性的研究进展[J]. 国际口腔医学杂志, 2023, 50(6): 632-638. |
[2] | 于乐蓉,李祥伟,艾虹. 牙髓干细胞干性维持的研究进展[J]. 国际口腔医学杂志, 2023, 50(4): 463-471. |
[3] | 王婧妍,秦满,王欣. Axenfeld-Rieger综合征的口腔颌面部临床特点及相关成对同源结构域转录因子2基因突变的致病机制研究进展[J]. 国际口腔医学杂志, 2023, 50(2): 224-229. |
[4] | 龚涛,李雨庆,周学东. 变异链球菌糖转运及其调控机制的研究进展[J]. 国际口腔医学杂志, 2022, 49(5): 506-510. |
[5] | 赵曼竹,宋锦璘. 时钟基因在牙齿发育中表达分布与调控机制的研究进展[J]. 国际口腔医学杂志, 2022, 49(4): 380-385. |
[6] | 王冠儒,冯强. 牙龈卟啉单胞菌在阿尔兹海默症发生中作用的研究进展[J]. 国际口腔医学杂志, 2022, 49(4): 397-403. |
[7] | 雷彬,陈柯. 牙本质发育不良Ⅰ型及其分型治疗[J]. 国际口腔医学杂志, 2022, 49(3): 332-336. |
[8] | 李俊霖,肖立伟. 隐形矫治技术推磨牙远移机制与疗效的研究进展[J]. 国际口腔医学杂志, 2022, 49(1): 109-115. |
[9] | 付琢惠,谭学莲,黄定明. 牙源性上颌窦炎的诊疗策略[J]. 国际口腔医学杂志, 2021, 48(3): 367-372. |
[10] | 赵文俊,郝晓琪,王凯利,刘媛媛,唐蓓,任家银,郑广宁. 对吻磨牙的研究进展[J]. 国际口腔医学杂志, 2021, 48(1): 96-101. |
[11] | 郏乐铭,贾小玥,杨燃,周学东,徐欣. 益生菌制剂在牙周病防治中的应用进展[J]. 国际口腔医学杂志, 2020, 47(5): 515-521. |
[12] | 杨佩佩,杨羽晨,张强. 尼古丁对牙槽骨破骨细胞的作用及其机制的研究进展[J]. 国际口腔医学杂志, 2020, 47(5): 616-620. |
[13] | 孔利心,任彪,程磊. 环氧合酶2/前列腺素E2通路调控口腔肿瘤机制的研究进展[J]. 国际口腔医学杂志, 2020, 47(4): 431-438. |
[14] | 刘琳,周婕妤,吴亚菲,赵蕾. 益生菌生态调节在牙周病防治中的应用[J]. 国际口腔医学杂志, 2020, 47(2): 131-137. |
[15] | 黄萧瑜,李明云,周学东,程磊. 全身及局部因素对种植体周围稳态的影响[J]. 国际口腔医学杂志, 2019, 46(6): 730-734. |
|