国际口腔医学杂志 ›› 2020, Vol. 47 ›› Issue (3): 356-361.doi: 10.7518/gjkq.2020065
Tian Guoli,Jiang Lu,Chen Qianming,Zeng Xin()
摘要:
味觉异常是一种以味觉异常变化为特征的疾病,易导致患者出现食欲不振、体重减轻、营养不良,严重时甚至影响其身心健康,使其生活质量降低。味觉异常的病因、发病机制尚不明确,可能的致病因素较繁杂,目前尚无公认有效的检查方法和治疗方式。该类患者大多选择先于口腔科就诊。本文总结了现有研究下的味觉异常的定义、分类、病因、检查方法、治疗方式、预后,以及常见的伴发于其他疾病的味觉异常,为口腔临床医生对于该类患者的诊疗提供备选方案。
中图分类号:
[1] |
Geran R, Uecker FC, Prüss H , et al. Olfactory and gustatory dysfunction in patients with autoimmune encephalitis[J]. Front Neurol, 2019,10:480.
doi: 10.3389/fneur.2019.00480 pmid: 31156532 |
[2] | Lee EJ, Park WK, Nam JW , et al. Clinical charac-teristics of patients with taste disorders[J]. J Oral Med Pain, 2009,34(4):341-351. |
[3] |
Walliczek-Dworschak U, Schöps F, Feron G , et al. Differences in the density of fungiform papillae and composition of saliva in patients with taste disorders compared to healthy controls[J]. Chem Senses, 2017,42(8):699-708.
doi: 10.1093/chemse/bjx054 pmid: 28981826 |
[4] |
Cowart BJ . Taste dysfunction: a practical guide for oral medicine[J]. Oral Dis, 2011,17(1):2-6.
doi: 10.1111/j.1601-0825.2010.01719.x pmid: 20796233 |
[5] |
Welge-Lüssen A . Re-establishment of olfactory and taste functions[J]. GMS Curr Top Otorhinolaryngol Head Neck Surg, 2005,4: Doc06.
pmid: 22073054 |
[6] |
Abu Bakr Elshafey Abd Elraouf, Hesham Abd El-Rahman, Ahmed Mohammed Mohammed El Refai , et al. Smell and taste disorders; recent management approaches[J]. J Am Sci, 2017,13(10):74-84.
doi: 10.2174/0929867325666180105102447 pmid: 29303074 |
[7] |
Syed Q, Hendler KT, Koncilja K . KThe impact of aging and medical status on dysgeusia[J]. Am J Med, 2016,129(7):753.e1-753.e6.
doi: 10.1016/j.amjmed.2016.02.003 pmid: 26899755 |
[8] |
Jetté M, Anderson C, Ramakrishnan V . Case report: diagnosis of hypogeusia after oral exposure to com-mercial cleaning agent and considerations for clinical taste testing[J]. F1000Res, 2017(6):373.
doi: 10.12688/f1000research.11241.2 pmid: 28713552 |
[9] |
van der Werf A, Rovithi M, Langius JAE , et al. In-sight in taste alterations during treatment with pro-tein kinase inhibitors[J]. Eur J Cancer, 2017,86:125-134.
doi: 10.1016/j.ejca.2017.09.006 pmid: 28987769 |
[10] |
Bergdahl M, Bergdahl J . Perceived taste disturbance in adults: prevalence and association with oral and psychological factors and medication[J]. Clin Oral Investig, 2002,6(3):145-149.
doi: 10.1007/s00784-002-0169-0 pmid: 12271346 |
[11] |
Kolkka-Palomaa M, Jääskeläinen SK, Laine MA , et al. Pathophysiology of primary burning mouth syn-drome with special focus on taste dysfunction: a review[J]. Oral Dis, 2015,21(8):937-948.
doi: 10.1111/odi.12345 pmid: 25962669 |
[12] |
Doty RL . Gustation[J]. Wiley Interdiscip Rev Cogn Sci, 2012,3(1):29-46.
doi: 10.1002/wcs.156 pmid: 26302471 |
[13] |
Mauri-Obradors E, Estrugo-Devesa A, Jané-Salas E , et al. Oral manifestations of diabetes mellitus. A systematic review[J]. Med Oral Patol Oral Cir Bucal, 2017,22(5):e586-e594.
doi: 10.4317/medoral.21655 pmid: 28809366 |
[14] |
Othieno F, Schlosser RJ, Rowan NR , et al. Taste impairment in chronic rhinosinusitis[J]. Int Forum Allergy Rhinol, 2018,8(7):783-789.
doi: 10.1002/alr.22113 pmid: 29569385 |
[15] |
Fitzgerald C, Wiese G, Moorthi RN , et al. Charac-terizing dysgeusia in hemodialysis patients[J]. Chem Senses, 2019,44(3):165-171.
doi: 10.1093/chemse/bjz001 pmid: 30629153 |
[16] |
Chandna S, Bathla M . Oral manifestations of thyroid disorders and its management[J]. Indian J Endocrinol Metab, 2011,15(Suppl 2):S113-S116.
doi: 10.4103/2230-8210.83343 pmid: 21966646 |
[17] |
Jajam M, Bozzolo P, Niklander S . Oral manifestations of gastrointestinal disorders[J]. J Clin Exp Dent, 2017,9(10):e1242-e1248.
doi: 10.4317/jced.54008 pmid: 29167716 |
[18] |
Noel C, Dando R . The effect of emotional state on taste perception[J]. Appetite, 2015,95:89-95.
doi: 10.1016/j.appet.2015.06.003 pmid: 26122754 |
[19] |
Methven L, Allen VJ, Withers CA , et al. Ageing and taste[J]. Proc Nutr Soc, 2012,71(4):556-565.
doi: 10.1017/S0029665112000742 pmid: 22883349 |
[20] |
Martin LJ, Sollars SI . Contributory role of sex dif-ferences in the variations of gustatory function[J]. J Neurosci Res, 2017,95(1/2):594-603.
doi: 10.1002/jnr.23819 pmid: 27870442 |
[21] |
Murtaza B, Hichami A, Khan AS , et al. Alteration in taste perception in cancer: causes and strategies of treatment[J]. Front Physiol, 2017,8:134.
doi: 10.3389/fphys.2017.00134 pmid: 28337150 |
[22] | Giacomelli A, Pezzati L, Conti F , et al. Self-reported olfactory and taste disorders in SARS-CoV-2 patients: a cross-sectional study[J]. Clin Infect Dis, 2020. doi: 10.1093/cid/ciaa330. |
[23] |
Just T, Steiner S, Pau HW . Oral pain perception and taste in burning mouth syndrome[J]. J Oral Pathol Med, 2010,39(1):22-27.
doi: 10.1111/j.1600-0714.2009.00824.x pmid: 19804504 |
[24] |
Imamura Y, Shinozaki T, Okada-Ogawa A , et al. An updated review on pathophysiology and management of burning mouth syndrome with endocrinological, psychological and neuropathic perspectives[J]. J Oral Rehabil, 2019,46(6):574-587.
doi: 10.1111/joor.12795 pmid: 30892737 |
[25] |
Braud A, Descroix V, Ungeheuer MN , et al. Taste function assessed by electrogustometry in burning mouth syndrome: a case-control study[J]. Oral Dis, 2017,23(3):395-402.
doi: 10.1111/odi.12630 pmid: 28029722 |
[26] |
Deshpande TS, Blanchard P, Wang L , et al. Radia-tion-related alterations of taste function in patients with head and neck cancer: a systematic review[J]. Curr Treat Options Oncol, 2018,19(12):72.
doi: 10.1007/s11864-018-0580-7 pmid: 30411162 |
[27] | Ponticelli E, Clari M, Frigerio S , et al. Dysgeusia and health-related quality of life of cancer patients receiving chemotherapy: a cross-sectional study[J]. Eur J Cancer Care (Engl), 2017,26(2). DOI: 10.1111/ecc.12633. |
[28] |
Negi P, Kingsley PA, Thomas M , et al. Pattern of gustatory impairment and its recovery after head and neck irradiation[J]. Iran J Otorhinolaryngol, 2017,29(95):319-327.
pmid: 29383312 |
[29] |
Sato T, Konuma T, Miwa Y , et al. A cross-sectional study on late taste disorders in survivors of allo-geneic hematopoietic cell transplantation[J]. Ann Hematol, 2017,96(11):1841-1847.
doi: 10.1007/s00277-017-3087-6 pmid: 28815326 |
[30] |
de Vries YC, Boesveldt S, Kelfkens CS , et al. Taste and smell perception and quality of life during and after systemic therapy for breast cancer[J]. Breast Cancer Res Treat, 2018,170(1):27-34.
doi: 10.1007/s10549-018-4720-3 pmid: 29476290 |
[31] |
Hummel T, Landis BN, Hüttenbrink KB . Smell and taste disorders[J]. GMS Curr Top Otorhinolaryngol Head Neck Surg, 2011,10:Doc04.
doi: 10.3205/cto000077 pmid: 22558054 |
[32] | Cormie SE, Hirsch AR . 74 alpha lipoic acid respon-sive hypergeusia[J]. CNS Spectr, 2019,24(1):212-213. |
[33] |
Kumbargere Nagraj S, George RP, Shetty N , et al. Interventions for managing taste disturbances[J]. Cochrane Database Syst Rev, 2017,12:CD010470.
doi: 10.1002/14651858.CD010470.pub3 pmid: 29260510 |
[34] |
Spanemberg JC, Segura-Egea JJ, Rodríguez-de Rivera-Campillo E , et al. Low-level laser therapy in patients with burning mouth syndrome: a double-blind, randomized, controlled clinical trial[J]. J Clin Exp Dent, 2019,11(2):e162-e169.
doi: 10.4317/jced.55517 pmid: 30805121 |
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