国际口腔医学杂志 ›› 2017, Vol. 44 ›› Issue (2): 195-199.doi: 10.7518/gjkq.2017.02.016
王玉霞,周学东,李明云
Wang Yuxia, Zhou Xuedong, Li Mingyun.
摘要: 韦荣球菌为口腔微生态的重要成员之一,在人类口腔中呈高丰度分布。韦荣球菌不能代谢糖产酸,但能代谢乳酸,这一点曾被认为对龋病的发生发展有抑制作用,但体外及动物试验对于韦荣球菌在龋病发生中的作用及其机制并未得出明确结论。近来随着口腔微生物组学研究的发展,人们发现,韦荣球菌在龋活跃者口腔中的分布较无龋者高,韦荣球菌与多种致龋菌分布呈高度相关性,韦荣球菌对变异链球菌等致龋菌有促进作用。龋病是多种微生物共同作用的结果,而韦荣球菌作为龋病相关因素不容忽视。本文就韦荣球菌在口腔中的分布、韦荣球菌与龋病的关系、韦荣球菌与链球菌的相互作用等研究进展作一综述,以剖析韦荣球菌在龋病发生发展中的作用及其机制。
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