国际口腔医学杂志 ›› 2017, Vol. 44 ›› Issue (1): 87-91.doi: 10.7518/gjkq.2017.01.018

• ·综述· • 上一篇    下一篇

破骨细胞蛋白酪氨酸磷酸酶与正畸移动牙牙根吸收的关系

崔跃, 姜欢, 胡敏   

  1. 吉林大学口腔医院正畸科 长春 130021
  • 收稿日期:2016-05-01 出版日期:2017-01-01 发布日期:2017-01-01
  • 通讯作者: 胡敏,教授,博士,Email:ydhhm@sohu.com
  • 作者简介:崔跃,硕士,Email:yue303994957@hotmail.com
  • 基金资助:
    国家自然科学基金(81470764)

The relationship between osteoclastic protein-tyrosine phosphatase and orthodontic treatment induced root resorption

Cui Yue, Jiang Huan, Hu Min.   

  1. Dept. of Orthodontics, Hospital of Stomatology, Jilin University, Changchun 130021, China
  • Received:2016-05-01 Online:2017-01-01 Published:2017-01-01

摘要: 牙根吸收是正畸治疗过程中一种常见的并发症,影响正畸牙牙根吸收的因素十分复杂。牙根吸收的过程与骨吸收过程相似,由与破骨细胞形态相似功能相仿的破牙骨质细胞发挥主要作用。破骨细胞蛋白酪氨酸磷酸酶(PTP-oc)主要在破骨细胞中表达,且对破骨细胞具有正调节作用。本文探讨PTP-oc的作用机制,旨在为防治牙根吸收提供一定的参考依据。

关键词: 牙根吸收, 破骨细胞蛋白酪氨酸磷酸酶, 作用机制

Abstract: Root resorption is a common complication of orthodontic treatment whose factors are very complicated. The processe of root resorption is similar to bone resorption. The cementoclast plays a main role in this process, and it is similar to the shape and function of osteoclasts. Osteoclastic protein-tyrosine phosphatase(PTP-oc) is mainly expressed in osteoclasts, and has a positive regulatory effect on osteoclasts. In this paper, the mechanism of PTP-oc is discussed, which provides a reference for the prevention and treatment of root resorption.

Key words: root resorption, osteoclastic protein-tyrosine phosphatase, mechanism of action

中图分类号: 

  • Q55
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