国际口腔医学杂志 ›› 2020, Vol. 47 ›› Issue (5): 595-600.doi: 10.7518/gjkq.2020096

• 综述 • 上一篇    下一篇

自伤性口腔溃疡的病因和临床诊疗特点

岳金涵(),王非,辛川,尹凤英,陈谦明,曾昕()   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院黏膜病科 成都 610041
  • 收稿日期:2020-02-05 修回日期:2020-06-02 出版日期:2020-09-01 发布日期:2020-09-16
  • 通讯作者: 曾昕
  • 作者简介:岳金涵,住院医师,硕士,Email: 1841486468@qq.com
  • 基金资助:
    国家自然科学基金(81771081)

Factitious oral ulcer: causes, clinical characteristics, and treatment

Yue Jinhan(),Wang Fei,Xin Chuan,Yin Fengying,Chen Qianming,Zeng Xin()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral Mucosal Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2020-02-05 Revised:2020-06-02 Online:2020-09-01 Published:2020-09-16
  • Contact: Xin Zeng
  • Supported by:
    National Natural Science Foundation of China(81771081)

摘要:

自伤性口腔溃疡属于创伤性口腔溃疡的一种,多认为是由于不良习惯、自伤性行为导致的口腔黏膜溃疡性改变。本文回顾总结了自伤性口腔溃疡的流行病学特点、临床表现、分型、病理学特征等内容,重点归纳分析了自伤性口腔溃疡的病因及诊疗特点,旨在强调精神心理行为异常在本疾病诊断、鉴别诊断、治疗等中的作用,为临床医生提供清晰、规范化的诊疗思路。

关键词: 自伤性口腔溃疡, 不良习惯, 自伤行为, 精神心理行为, 注意缺陷多动障碍, 抽动障碍

Abstract:

Factitious oral ulcer is a kind of traumatic oral ulcer that is caused by harmful habits or self-injurious behaviors. In this article, we reviewed and summarized the epidemiological characteristics, clinical manifestations, classification, and pathological characteristics of factitious oral ulcer. We mainly focused on the etiology, diagnosis, and treatment characteristics to emphasize the essential role of abnormal mental and psychological behaviors in the diagnosis, differential diagnosis, and treatment of the disease. Results of this study can help provide clear and standardized diagnosis and treatment ideas for clinicians.

Key words: factitious oral ulcer, deleterious habit, self-injurious behavior, mental and psychological behavior, attention-deficit hyperactivity disorder, tic disorder

中图分类号: 

  • R781.5+1

表 1

精神心理疾病筛查常用量表"

量表名称 适用人群 筛查目的
Achenbach儿童行为量表[36] 4~18岁的儿童及青少年 用于评估儿童各种精神病理学疾病,覆盖广泛
Conners父母症状问卷[37] 3~17岁儿童及青少年 用于评估儿童行为问题,特别是ADHD
SNAP-Ⅳ量表[38,39] 儿童及青少年ADHD患者 用于评估ADHD病情
Rutter儿童行为问卷 学龄期儿童 用于评估儿童的情绪、行为及精神问题
成人ADHD症状自评量表 成年人 用于成人ADHD筛查
[1] 陈谦明. 口腔黏膜病学[M]. 4版. 北京: 人民卫生出版社, 2012: 79-80.
Chen QM. Oral mucosal diseases[M]. 4th ed. Beijing: People’s Medical Publishing House, 2012: 79-80.
[2] 金早蓉, 秦念红, 蔡淦英. 深圳市儿童口腔黏膜病173例临床分析[J]. 齐齐哈尔医学院学报, 2013,34(8):1129-1130.
Jin ZR, Qin NH, Cai GY . Clinical analysis of 173 cases of oral mucosal disease in children in Shenzhen[J]. J Qiqihar Med Coll, 2013,34(8):1129-1130.
[3] Amadori F, Bardellini E, Conti G, et al. Oral mucosal lesions in teenagers: a cross-sectional study[J]. Ital J Pediatr, 2017,43(1):50.
doi: 10.1186/s13052-017-0367-7 pmid: 28569171
[4] Kashyap RR, Kashyap RS. Self-inflicted injury as a potential trigger for carcinoma of lip—a case report[J]. Gerodontology, 2013,30(3):236-238.
doi: 10.1111/ger.12009
[5] Nico MM, Nagano CP, Fernandes JD, et al. A destruc-tive ulcer on the lower lip[J]. Clin Exp Dermatol, 2010,35(4):e180-e181.
pmid: 20518908
[6] 王炫, 殷操. 自伤性溃疡与儿童心理行为相关因素的临床分析[J]. 现代医院, 2011,11(1):9-10.
Wang X, Yin C . Clinical analysis of self-inflicted ulcers and children’s psychological and behavioral factors[J]. Mod Hosp, 2011,11(1):9-10.
[7] Rajchanovska D, Zafirova-Ivanovska B. Oral habits among pre-elementary children in Bitola[J]. Prilozi, 2012,33(1):157-169.
pmid: 22952102
[8] Garde JB, Suryavanshi RK, Jawale BA, et al. An epidemiological study to know the prevalence of deleterious oral habits among 6 to 12 year old children[J]. J Int Oral Health, 2014,6(1):39-43.
pmid: 24653601
[9] Thapar A, Cooper M. Attention deficit hyperactivity disorder[J]. Lancet, 2016,387(10024):1240-1250.
doi: 10.1016/S0140-6736(15)00238-X pmid: 26386541
[10] Ogundele MO. Behavioural and emotional disorders in childhood: a brief overview for paediatricians[J]. World J Clin Pediatr, 2018,7(1):9-26.
pmid: 29456928
[11] Halicka J, Kiejna A. Non-suicidal self-injury (NSSI) and suicidal: criteria differentiation[J]. Adv Clin Exp Med, 2018,27(2):257-261.
doi: 10.17219/acem/66353 pmid: 29521070
[12] Saemundsson SR, Roberts MW. Oral self-injurious behavior in the developmentally disabled: review and a case[J]. ASDC J Dent Child, 1997,64(3):205-209, 228.
pmid: 9262803
[13] Whitbeck LB, Chen XJ, Hoyt DR, et al. Mental disorder, subsistence strategies, and victimization among gay, lesbian, and bisexual homeless and run-away adolescents[J]. J Sex Res, 2004,41(4):329-342.
pmid: 15765273
[14] Limeres J, Feijoo JF, Baluja F, et al. Oral self-injury: an update[J]. Dent Traumatol, 2013,29(1):8-14.
doi: 10.1111/j.1600-9657.2012.01121.x pmid: 22340154
[15] Stewart DJ, Kernohan DC. Self-inflicted gingival injuries. Gingivitis artefacta, factitial gingivitis[J]. Dent Pract Dent Rec, 1972,22(11):418-426.
pmid: 4507270
[16] Kotansky K, Goldberg M, Tenenbaum HC, et al. Factitious injury of the oral mucosa: a case series[J]. J Periodontol, 1995,66(3):241-245.
pmid: 7776171
[17] Zonuz AT, Treister N, Mehdipour F, et al. Factitial pemphigus-like lesions[J]. Med Oral Patol Oral Cir Bucal, 2007,12(3):E205-E208.
pmid: 17468715
[18] Subbaiah R, Biju TMD, Maithreyi VP. Self-inflicted traumatic injuries of the gingiva: a case series[J]. Int Oral Health, 2010,2(2):43-49.
[19] Medina AC, Sogbe R, Gómez-Rey AM, et al. Factitial oral lesions in an autistic paediatric patient[J]. Int J Paediatr Dent, 2003,13(2):130-137.
doi: 10.1046/j.1365-263x.2003.00440.x pmid: 12605633
[20] Hildebrand LC, Carvalho AL, da Rosa FM, et al. Functional oral self-mutilation in physically healthy pediatric patients: case report and analysis of 27 lite-rature cases[J]. Int J Pediatr Otorhinolaryngol, 2011,75(6):880-883.
doi: 10.1016/j.ijporl.2011.03.020 pmid: 21513990
[21] Harris D. Factitious buccal lesion secondary to bruxism in a child with cerebral palsy[J]. Emerg Med J, 2006,23(1):e4.
doi: 10.1136/emj.2004.020073 pmid: 16373789
[22] 胡晓杰, 王玉, 杨芝芳. 95例儿童自伤性溃疡临床分析[J]. 中国现代医生, 2008,46(15):245-246.
Hu XJ, Wang Y, Yang ZF . Clinical analysis of 95 cases of factitious ulcer in children[J]. China Mod Doc, 2008,46(15):245-246.
[23] Gunduz A, Okun MS. A review and update on tou-rette syndrome: where is the field headed[J]. Curr Neurol Neurosci Rep, 2016,16(4):37.
doi: 10.1007/s11910-016-0633-x pmid: 26936259
[24] Robertson MM. The Gilles de la Tourette syndrome: the current status[J]. Arch Dis Child Educ Pract Ed, 2012,97(5):166-175.
pmid: 22440810
[25] Whittington C, Pennant M, Kendall T, et al. Practi-tioner review: treatments for Tourette syndrome in children and young people—a systematic review[J]. J Child Psychol Psychiatry, 2016,57(9):988-1004.
pmid: 27132945
[26] Gonçalves PS, Mendez DA, Santos PS, et al. The diagnosis and treatment of multiple factitious oral ulcers in a 6-year-old boy[J]. Case Rep Dent, 2017,2017:1986834.
pmid: 28293440
[27] Rowland AS, Skipper BJ, Umbach DM, et al. The prevalence of ADHD in a population-based sample[J]. J Atten Disord, 2015,19(9):741-754.
doi: 10.1177/1087054713513799 pmid: 24336124
[28] Willcutt EG. The prevalence of DSM-IV attention-deficit/hyperactivity disorder: a meta-analytic review[J]. Neurotherapeutics, 2012,9(3):490-499.
doi: 10.1007/s13311-012-0135-8
[29] Mohr-Jensen C, Steinhausen HC. A meta-analysis and systematic review of the risks associated with childhood attention-deficit hyperactivity disorder on long-term outcome of arrests, convictions, and in-carcerations[J]. Clin Psychol Rev, 2016,48:32-42.
pmid: 27390061
[30] Wood DR, Reimherr FW, Wender PH, et al. Diagnosis and treatment of minimal brain dysfunction in adults: a preliminary report[J]. Arch Gen Psychiatry, 1976,33(12):1453-1460.
pmid: 793563
[31] Ustun B, Adler LA, Rudin C, et al. The world health organization adult attention-deficit/hyperactivity disorder self-report screening scale for DSM-5[J]. JAMA Psychiatry, 2017,74(5):520-527.
pmid: 28384801
[32] Nigg JT, Knottnerus GM, Martel MM, et al. Low blood lead levels associated with clinically diagnosed attention-deficit/hyperactivity disorder and mediated by weak cognitive control[J]. Biol Psychiatry, 2008,63(3):325-331.
pmid: 17868654
[33] Kim S, Arora M, Fernandez C, et al. Lead, mercury, and cadmium exposure and attention deficit hype-ractivity disorder in children[J]. Environ Res, 2013,126:105-110.
doi: 10.1016/j.envres.2013.08.008
[34] Lepping P, Huber M. Role of zinc in the pathogenesis of attention-deficit hyperactivity disorder: implica-tions for research and treatment[J]. CNS Drugs, 2010,24(9):721-728.
doi: 10.2165/11537610-000000000-00000 pmid: 20806985
[35] Oner O, Alkar OY, Oner P. Relation of ferritin levels with symptom ratings and cognitive performance in children with attention deficit-hyperactivity disorder[J]. Pediatr Int, 2008,50(1):40-44.
pmid: 18279203
[36] van Meter A, Youngstrom E, Youngstrom JK, et al. Clinical decision making about child and adolescent anxiety disorders using the Achenbach system of empirically based assessment[J]. J Clin Child Adolesc Psychol, 2014,43(4):552-565.
pmid: 24697608
[37] 苏林雁, 李雪荣, 黄春香, 等. Conners父母症状问卷的中国城市常模[J]. 中国临床心理学杂志, 2001,9(4):241-243, 252.
Su LY, Li XR, Huang CX , et al. Norms of the conners parent symptom questionnaire in Chinese urban children[J]. Chin J Clin Psychol, 2001,9(4):241-243, 252.
[38] 张慧凤, 张劲松, 帅澜, 等. 学龄前儿童中文版SNAP-Ⅳ评定量表父母版的信效度检验[J]. 中国儿童保健杂志, 2016,24(12):1253-1256.
Zhang HF, Zhang JS, Shuai L , et al. Reliability and validity of the Chinese version of the Swanson, Nolan, and Pelham, version Ⅳ scale-parent form[J]. Chin J Child Heal Care, 2016,24(12):1253-1256.
[39] Tsai CJ, Chen YL, Lin HY, et al. One-year trajectory analysis for ADHD symptoms and its associated factors in community-based children and adolescents in Taiwan[J]. Child Adolesc Psychiatry Ment Health, 2017,11:28.
doi: 10.1186/s13034-017-0165-4 pmid: 28580012
[40] Kwon IJ, Kim SM, Park HK, et al. Successful treat-ment of self-inflicted tongue trauma patient using a special oral appliance[J]. Int J Pediatr Otorhinolaryngol, 2015,79(11):1938-1941.
doi: 10.1016/j.ijporl.2015.08.013 pmid: 26315926
[41] Munerato MC, Moure SP, Machado V, et al. Self-mutilation of tongue and lip in a patient with simple schizophrenia[J]. Clin Med Res, 2011,9(1):42-45.
doi: 10.3121/cmr.2010.930 pmid: 20852088
[42] Arhakis A, Topouzelis N, Kotsiomiti E, et al. Effective treatment of self-injurious oral trauma in Lesch-Nyhan syndrome: a case report[J]. Dent Traumatol, 2010,26(6):496-500.
doi: 10.1111/j.1600-9657.2010.00930.x pmid: 21078074
[43] 周曾同. 口腔黏膜病疑难病案分析[M]. 北京: 中国中医药出版社, 2015: 92-96.
Zhou ZT. Analysis of difficult cases of oral mucosal disease[M]. Beijing: Chinese Medicine Publishing House, 2015: 92-96.
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