国际口腔医学杂志 ›› 2019, Vol. 46 ›› Issue (5): 552-557.doi: 10.7518/gjkq.2019053
Jiang Xiaoge1,Wu Jiaxin1,Pei Xibo2()
摘要:
金属-有机骨架(MOF)也被称为配位聚合物,是一种新型的有机-无机杂化晶态多孔材料,由金属离子或者金属离子簇作为节点,多配位点的有机配体作为连接点,通过配位作用自组装形成高度规则的网状骨架结构。MOF及复合材料的特殊性能促进其在生物医学领域的应用,包括种植体表面涂层改性、药物载体、储存气体、辅助生物体内显影成像等。本文对MOF材料在生物医学领域以上几个方面应用的研究情况进行综述。
中图分类号:
[1] | Chernikova V, Shekhah O, Eddaoudi M . Advanced fabrication method for the preparation of MOF thin films: liquid-phase epitaxy approach meets spin coating method[J]. ACS Appl Mater Interfaces, 2016,8(31):20459-20464. |
[2] | Furukawa H, Müller U, Yaghi OM . “Heterogeneity within order” in metal-organic frameworks[J]. Angew Chem Int Ed Engl, 2015,54(11):3417-3430. |
[3] | Hoskins BF, Robson R . Infinite polymeric frameworks consisting of three dimensionally linked rod-like segments[J]. J Am Chem Soc, 1989,111(15):5962-5964. |
[4] | Civantos A , MartínezCampos E, Ramos V, et al. Titanium coatings surface modifications: toward clinically useful bioactive implants[J]. ACS Biomater Sci Eng, 2017,3(7):1245-1261. |
[5] | Yurttutan ME, Keskin A . Evaluation of the effects of different sand particles that used in dental implant roughened for osseointegration[J]. BMC Oral Health, 2018,18(1):47. |
[6] | Brunetto PS, Slenters TV, Fromm KM . In vitro biocompatibility of new silver (Ⅰ) coordination compound coated-surfaces for dental implant applications[J]. Materials (Basel), 2011,4(2):355-367. |
[7] | Chen J, Zhang X, Huang C , et al. Osteogenic activity and antibacterial effect of porous titanium modified with metal-organic framework films[J]. J Biomed Mater Res A, 2017,105(3):834-846. |
[8] | Zhang X, Chen J, Pei X , et al. Enhanced osseointegration of porous titanium modified with zeolitic imidazolate framework-8[J]. ACS Appl Mater Interfaces, 2017,9(30):25171-25183. |
[9] | Gao X, Hai X, Baigude H , et al. Fabrication of functional hollow microspheres constructed from MOF shells: promising drug delivery systems with high loading capacity and targeted transport[J]. Sci Rep, 2016,6:37705. |
[10] | Shu F, Lv D, Song XL , et al. Fabrication of a hyaluronic acid conjugated metal organic framework for targeted drug delivery and magnetic resonance imaging[J]. Rsc Advances, 2018,8(12):6581-6589. |
[11] | Sun CY, Qin C, Wang XL , et al. Metal-organic frameworks as potential drug delivery systems[J]. Expert Opin Drug Deliv, 2013,10(1):89-101. |
[12] | Horcajada P, Serre C, Vallet-Regí M , et al. Metal-organic frameworks as efficient materials for drug delivery[J]. Angew Chem Int Ed Engl, 2006,45(36):5974-5978. |
[13] | Tan LL, Li H, Qiu YC , et al. Stimuli-responsive metal-organic frameworks gated by pillar[5]arene supramolecular switches[J]. Chem Sci, 2015,6(3):1640-1644. |
[14] | Wu YN, Zhou M, Li S , et al. Magnetic metal-organic frameworks: γ-Fe2O3@MOFs via confined in situ pyrolysis method for drug delivery[J]. Small, 2014,10(14):2927-2936. |
[15] | Ke F, Yuan YP, Qiu LG , et al. Facile fabrication of magnetic metal-organic framework nanocomposites for potential targeted drug delivery[J]. J Mater Chem, 2011,21(11):3843-3848. |
[16] | Cunha D, Yahia MB, Hall S , et al. Rationale of drug encapsulation and release from biocompatible porous metal-organic frameworks[J]. Chem Mater, 2013,25(14):2767-2776. |
[17] | Zhu X, Gu J, Wang Y , et al. Inherent anchorages in UiO-66 nanoparticles for efficient capture of alendronate and its mediated release[J]. Chem Commun (Camb), 2014,50(63):8779-8782. |
[18] | He C, Lu K, Liu D , et al. Nanoscale metal-organic frameworks for the co-delivery of cisplatin and pooled siRNAs to enhance therapeutic efficacy in drug-resistant ovarian cancer cells[J]. J Am Chem Soc, 2014,136(14):5181-5184. |
[19] | Lucena FR, de Araújo LC, Rodrigues Mdo D , et al. Induction of cancer cell death by apoptosis and slow release of 5-fluoracil from metal-organic frameworks Cu-BTC[J]. Biomed Pharmacother, 2013,67(8):707-713. |
[20] | Au KM, Satterlee A, Min Y , et al. Folate-targeted pH-responsive calcium zoledronate nanoscale metal-organic frameworks: turning a bone antiresorptive agent into an anticancer therapeutic[J]. Biomaterials, 2016,82:178-193. |
[21] | Chowdhuri AR, Laha D, Chandra S , et al. Synjournal of multifunctional upconversion NMOFs for targeted antitumor drug delivery and imaging in triple negative breast cancer cells[J]. Chem Eng J, 2017,319(Complete):200-211. |
[22] | Nabipour H, Soltani B, Ahmadi Nasab N . Gentamicin loaded Zn2(bdc)2(dabco) frameworks as efficient materials for drug delivery and antibacterial activity[J]. J Inorg Organomet P, 2018,28(3):1206-1213. |
[23] | Wo Y, Brisbois EJ, Bartlett RH , et al. Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO)[J]. Biomater Sci, 2016,4(8):1161-1183. |
[24] | Uzunova EL, Mikosch H . A theoretical study of nitric oxide adsorption and dissociation on copper-exchanged zeolites SSZ-13 and SAPO-34: the impact of framework acid-base properties[J]. Phys Chem Chem Phys, 2016,18(16):11233-11242. |
[25] | Xue C, Xu T . Metal-organic frameworks as host materials for storage and slow-releasing of medicinal nitric oxide[J]. Chemistry, 2013,76(12):1086-1090. |
[26] | Mckinlay AC, Xiao B, Wragg DS , et al. Exceptional behavior over the whole adsorption-storage-delivery cycle for NO in porous metal organic frameworks[J]. J Am Chem Soc, 2008,130(31):10440-10444. |
[27] | Khan AH, Barth B, Hartmann M , et al. Nitric oxide adsorption in MIL-100(Al) MOF studied by solid-state NMR[J]. J Phys Chem C, 2018,112(24):12723-12730. |
[28] | Xiao B, Wheatley PS, Zhao X , et al. High-capacity hydrogen and nitric oxide adsorption and storage in a metal-organic framework[J]. J Am Chem Soc, 2007,129(5):1203-1209. |
[29] | Katharina P, Frank H, Michael F , et al. Tuning the nitric oxide release behavior of amino functionalized HKUST-1[J]. Micropor Mesopor Mat, 2015,216:118-126. |
[30] | Nguyen JG, Tanabe KK, Cohen SM . Postsynthetic diazeniumdiolate formation and NO release from MOFs[J]. Cryst Eng Comm, 2010,12(8):2335-2338. |
[31] | Cohen SM . Postsynthetic methods for the functionalization of metal-organic frameworks[J]. Chem Rev, 2012,112(2):970-1000. |
[32] | Pinto RV, Antunes F, Pires J , et al. Vitamin B3 metal-organic frameworks as potential delivery vehicles for therapeutic nitric oxide[J]. Acta Biomater, 2017,51:66-74. |
[33] | Miller SE, Teplensky MH, Moghadam PZ , et al. Metal-organic frameworks as biosensors for luminescence-based detection and imaging[J]. Interface Focus, 2016,6(4):20160027. |
[34] | deKrafft KE, Xie Z, Cao G , et al. Iodinated nanoscale coordination polymers as potential contrast agents for computed tomography[J]. Angew Chem Int Ed Engl, 2009,48(52):9901-9904. |
[35] | Horcajada P, Chalati T, Serre C , et al. Porous metal-organic-framework nanoscale carriers as a potential platform for drug delivery and imaging[J]. Nat Mater, 2010,9(2):172-178. |
[36] | Zhou J, Tian G, Zeng L , et al. Nanoscaled metal-organic frameworks for biosensing, imaging, and cancer therapy[J]. Adv Healthc Mater, 2018,7(10):e1800022. |
[37] | Cai W, Gao H, Chu C , et al. Engineering phototheranostic nanoscale metal-organic frameworks for multimodal imaging-guided cancer therapy[J]. ACS Appl Mater Interfaces, 2017,9(3):2040-2051. |
[38] | Tian C, Zhu L, Lin F , et al. Poly(acrylic acid) bridged gadolinium metal-organic framework-gold nanoparticle composites as contrast agents for computed tomography and magnetic resonance bimodal imaging[J]. ACS Appl Mater Interfaces, 2015,7(32):17765-17775. |
[39] | Cai W, Gao H, Chu C , et al. Engineering phototheranostic nanoscale metal-organic frameworks for multimodal imaging-guided cancer therapy[J]. ACS Appl Mater Interfaces, 2017,9(3):2040-2051. |
[40] | Wang D, Zhou J, Chen R , et al. Controllable synjournal of dual-MOFs nanostructures for pH-responsive artemisinin delivery, magnetic resonance and optical dual-model imaging-guided chemo/photothermal combinational cancer therapy[J]. Biomaterials, 2016,100:27-40. |
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