国际口腔医学杂志 ›› 2017, Vol. 44 ›› Issue (3): 336-339.doi: 10.7518/gjkq.2017.03.017

• 综述 • 上一篇    下一篇

外泌体与口腔疾病关系的研究进展

吴佳梦, 王效英   

  1. 山东大学口腔医院牙体牙髓病科 山东省口腔组织再生重点实验室 济南 250012
  • 收稿日期:2016-10-12 修回日期:2017-01-11 出版日期:2017-05-01 发布日期:2017-05-01
  • 通讯作者: 王效英,副教授,博士,Email:xiaoyingwang@sdu.edu.cn
  • 作者简介:吴佳梦,硕士,Email:wjm199092@hotmail.com

Research progress on exosomes and oral diseases

Wu Jiameng, Wang Xiaoying.   

  1. Dept. of Conservative Dentistry and Endodontics, Hospital of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Rege-neration, Jinan 250012, China
  • Received:2016-10-12 Revised:2017-01-11 Online:2017-05-01 Published:2017-05-01

摘要: 外泌体是由各种类型的细胞分泌的多形性囊泡样小体,其中含有蛋白质和RNA等多种成分,具有抗肿瘤免疫、促血管新生等生理功能,并且与口腔疾病密切相关。外泌体可作为口腔癌、口腔黏膜病、唾液腺疾病等口腔疾病诊断的生物标志物,还有作为口腔癌候选抗癌疫苗的可能。本文主要就外泌体及其与口腔疾病的关系作一综述。

关键词: 外泌体, 口腔疾病, 生物标志物

Abstract: Exosomes secreted by various types of cells are small vesicular bodies that contain many types of proteins and RNAs. They have multiple functions, such as anti-tumor immunity and angiogenesis. Their possible use as oral disease biomarkers and vaccine candidates was also discussed. This review presents recent advances in exosomes and the relationship with oral diseases.

Key words: exosome, oral disease, biomarker

中图分类号: 

  • R781
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